GH secretagogue
CJC-1295 (with DAC)
Not approved; development stoppedSmall human studiesCJC-1295 DACDAC:GRF
A GHRH analog with a chemical tag (DAC) that binds it to albumin in the blood, so it lasts about a week. Small human studies in the mid-2000s showed it raised GH and IGF-1 for days after one injection. Development was stopped and it was never approved.
- Canada
- Not authorized
- United States
- Not approved
Download profile Opens in Vialchemy on your iPhone, where it's added to your Library as your own.
Not medical advice — talk to your doctor before making medical decisions.
At a glance
- Class
- GH secretagogue (long-acting GHRH analog)
- Mechanism
- Keeps GH and IGF-1 raised for days
- Evidence
- Small early human studies
- Canada
- Not authorized
- Us
- Not approved
- Half Life
- About 6-8 days
- Routes
- SubQ
- Common Side Effects
- Flushing, site reactions, headache, water retention
- Key Cautions
- Constant (not pulsed) GH raise; raised blood sugar; WADA prohibited
What the research says
What did human studies show?
In small 2006 studies in healthy adults, one injection raised GH for about 6 days and IGF-1 for about 9-11 days. They didn't measure long-term benefits or safety.
Why does the DAC matter?
It keeps GH raised all the time instead of in natural pulses. That's a different effect from the no-DAC version and is more likely to cause water retention and blood-sugar effects.
Mixing up DAC and no-DAC?
They're very different in how long they last. Make sure the vial, the app entry and any schedule all say the same version.
Common side effects and cautions
- Water retention, tingling or numb hands, joint aches and headache are the usual GH-related effects.
- Raised growth hormone and IGF-1 can raise blood sugar and lower insulin sensitivity. Worth watching if you're also on a GLP-1 or have prediabetes.
- Flushing, light-headedness or a rush of hunger right after injection are commonly reported.
- Long-term raised IGF-1 is linked in studies to cancer growth, so people with active cancer or a history of it are usually told to avoid GH-raising compounds.
- Prohibited in sport (WADA S2) if you're drug-tested.
Get medical care if
- Redness, heat, swelling or pus at a site that spreads or comes with fever
- Hives, swelling of the face or throat, or trouble breathing (call 911)
Buying and quality
- Not authorized by Health Canada. Products sold online as "research use only" are illegal to sell for human use in Canada, and the label doesn't change that.
- Health Canada warns these products may contain too much, too little or none of the peptide, plus contaminants like endotoxins, solvents, heavy metals or bacteria.
- A certificate of analysis (COA) from the seller isn't independent proof. A 98% purity result still leaves 2% unidentified.
- If you use it anyway: one clean needle per injection, sterile technique, label and date every vial, and stop if a site gets hot, red and spreading.
Dose calculator
Doses are set with your prescriber. This converts a dose you already have into what to draw; it doesn't recommend one. Check every number against your syringe and your vial's label.
Doses left in the vial
A blend vial
Not medical advice — talk to your doctor before making medical decisions.
Sources
Researched 2026-10-27. Trial results and approval status change.
General education, not medical advice. Nothing here is a dose recommendation. Doses, schedules and changes are set with a prescriber.